Il y a exactement 20 ans, AtlanChim Pharma était créée…

AtlanChim Pharma was founded in May 2004! Twenty years later, and over 2,000 contracts completed, we have our favorite reagents. For instance, we like to use Dess-Martin periodinane (DMP), also known as 1,1-dihydro-1,1,1-triacetoxy-1,2-benziodoxol-3-(1H)-one, for the oxidation of primary alcohols to aldehydes. [1] Nevertheless, we have observed some surprising side reactions, particularly in some cases with substrates containing a 1,2-diol motif. This behavior of DMP illustrated in the Scheme below, with an example taken from the literature [2], has been rarely reported. [3] 

[1] R. Varala, V. Seema, M. M. Alam, M. Amanullah, N. Dubasi, Curr. Org. Chem. 2023, 27, 1504-1530.
[2] W. Quan, B. Yu, J. Zhang, Q. Liang, X. Shea, X. Pan, Tetrahedron 2007, 63, 9991-9996.
[3] For another example, see: M. Enomoto, S. Kuwahara, J. Org. Chem. 2010, 75, 6286-6289.