Scientific letter N°9
AtlanChim Pharma is celebrating its 12th birthday! For this special event, Professor Jacques LEBRETON has chosen to highlight (site
specific) stable isotope labeling in his 9th scientific letter.
After 12 years of close collaboration with its customers, AtlanChim Pharma has synthesized more than 200 stable isotope labeled compounds (D, 13C, 15N et 34S) and has thus gained a strong expertise in that field. From heterocycle to chiral amino acids through steroids, the labeled compounds that we have synthetized for our customers represent most of all types of organic structures.
These multi-step synthesis (from one step up to more than ten steps) have been successfully performed at lab-scale – from mg up to several gr scale. It is clear that throughout all the difficulties we have encountered, overcome or circumvented, we have accumulated a unique know-how. Therefore we can offer tailor made solutions beyond the standard molecules that can be found in catalogs.
With more than 1200 projects handled since 2004, the expertise of our chemists, some of them being part of the company since its creation, is constantly enriched throughout their work in the stable isotope labeling field as well as their experience in more classical synthesis.
Regular reading of recently published studies is also a major asset and an essential scientific monitoring work. In this context, this new scientific letter makes us share the recent work of our industrial and academic colleagues in the field of stable isotope labeling.
Before you start reading this scientific letter, here are some news we wanted to share with you.
Our Atlanta group has chosen to implement Good Laboratory Practices on preclinical studies for Atlantic Bone Screen and on analytical method validation for AtlanChim Pharma. This complements the existing system ensuring traceability and control of our processes.
In addition, we acquired an automated purification system with UV detection (flash and semi-prep) and to complete our analytical services, a U-HPLC coupled with UV detector and charged aerosol detection to analyze molecules which are not UV visible.
Finally, you will find, like you did in our previous scientific letters, the portrait of two members of our team: Dr. Maud ANTOINE, our analytical specialist and Dr. Kevin FOURMY who joined us at the beginning of this year.
Happy reading everyone !
