Dr. Sylvie ARCHAMBAUD
PhD Defense in 2004: “Research in brefeldin A and C series: total synthesis of (+)-brefeldin C” (André Guingant, Nantes’ School of Science)
Post-Doctoral experience 2004-2005: “Study of concept of « chirality relay » in Diels-Alder reactions, catalyzed by chiral Lewis acids. Study of alcynes carbometallation with copper salts” (Philippe Renaud, Universität Bern, Department für Chemie und Biochemie)
Publications
“Imidazolone derivatives as DYRK1a/CLK1/CLK4 inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases”, EP4173674, WO2023072969.
“Total Synthesis of (+)-Brefeldin C, (+)-nor-Me Brefeldin A and (+)-4-epi-nor-Me Brefeldin A” Eur. J. Org. Chem., 2010, 7, 1364-1380.
“Enantioselective synthesis of an advanced intermediate for the synthesis of Brefeldin A and analogues” Synlett, 2008, 3, 389-393.
“Chemical biology and synthesis. The spring meeting of the swiss chemical society, March 10th, 2005, department of chemistry and biochemistry, university of bern” Chimia, 2005, 59, 267-268.
“A new total synthesis of (+)-Brefeldin C” Synlett, 2005, 1, 139-143.
